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00 Stem cells to be injected into heart attack patients 00

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Author : Philip Green

News Category : Health


LONDON - In a unique experimental trial British doctors plan to inject stem cells into heart attack patients in order to prevent heart failure and subsequent death. The study is expected to begin early next year and will have around 100 participants.

The patients will be injected with either their own stem cells from the bone marrow or with a placebo within five hours after suffering a heart attack. "We are hoping that the patients will have an increased quality of life six months after the procedure," said lead researcher Professor John Martin, of University College London.


Normal treatment that follows the conventional path will also be administered along with the stem cell therapy, scientists said. Stem cells are the starting point or the master cells from which all other functional cells are derived.

Scientists hoped that stem cells could be a major repair system when injected into the body of those suffering heart disease, diabetes and Alzheimer's disease, besides other diseases considered incurable at the present time. While the use of embryonic stem cells is controversial, scientists hope to avoid that by using the body's own stem cells.

"All other studies have put cells into the heart in small groups of patients several days or weeks after the heart attack," Martin told Reuters. Scientists are hoping that by quickly injecting stem cells, they will allow the heart muscle to be repaired before any irreversible damage is done.

In earlier trials stem cells have been injected days or weeks after a heart attack. In a trial on 28 participants by researchers from Australia and Hong Kong, it was found that injecting stem cells improved the pumping ability of the heart.

David Macauley, chief executive of the UK Stem Cell Foundation said that the benefits would be more if the treatment was given early, "This is the first project of its type in the UK to combine stem cell delivery to the heart with primary angioplasty – where the blocked arteries in heart attack patients are opened as quickly as possible," he said.

Professor Peter Weissberg, medical director of the British Heart Foundation, also welcome the new trial saying that stem cells could hold the key to helping heart patients in future.



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